Invasive secretory breast cancer

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It is called secretory breast carcinoma because of the abundant secretion of mucin within the tumor. It can occur over virtually all age ranges, but the average age of presentation is estimated at around 25 years. I just want to let you know that I have created a newer version of this page with more up-to-date information on Secretory Breast Cancer.

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Classification Note Considered to be a subtype of infiltrating ductal carcinoma of the breast, but associated with a better prognosis. Clinics and Pathology Embryonic origin Epithelial derived tumors, such as the breast carcinomasarise from the Ectoderm. Etiology Our index case only demonstrated a t 12;15 p13;q25 by cytogenetics, as seen in congenital fibrosarcoma CFS and the cellular variant of congenital mesoblastic nephroma cCMN.

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Secretory breast carcinoma is a very rare and distinct subtype of breast cancer, characterized by the presence of intracellular and extracellular secretory material. Secretory breast carcinoma has a good clinical outcome and systemic involvement is rare. The majority of studies of this tumor have been case reports or separate analyses, and due to the rarity of these tumors, it has been difficult to fully elucidate their characteristics and define optimal treatment strategies.

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Secretory breast carcinoma SBC is a rare and distinct variant of breast cancer, accounting for less than 0. However, it was later shown to occur in all age groups, and both men and women can be affected. SBC has been reported to display an immunophenotype with triple negativity. Because the diagnosis of this disease is comparatively limited, it is difficult to separate from other pathological types.

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Published: November 16, Int J Oncol Res This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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The lesions are typically solitary, but rare multicentric cases have been reported. SBC have characteristic histopathological, immunohistochemical, and electron microscopic findings. Children and adolescents with SBC have a favorable prognosis, but disease seems slightly more aggressive in adults.

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We present two cases treated with total mastectomy and sentinel node biopsy with excellent outcome. To our knowledge, only a few cases have been reported in Latin American patients. Desde ese momento aproximadamente casos han sido reportados en la literatura.

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Secretory carcinoma SC of the breast is a rare and indolent tumor. Although originally described in children, it is now known to occur in adults of both sexes. A year-old male was diagnosed with secretory breast carcinoma and underwent a modified radical mastectomy.

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Brief Case Report. Journal of Pathology and Translational Medicine ; 52 3 : Published online: October 4,

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Spotlight On Click here for issue 1, featuring our GI editor Dr. Raul Gonzalez.

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